The example I saw involved a system-level optimization of a PLL design. Results showed up as a trade-off curve between total power versus integrated noise.
The methodology to using Mephisto tools involves a 5 step process:
1) Capture design intent, specs, conditions, etc.
2) Compute circuit performance, multi-variable sweeps, control simulations, define types of analysis, sizing, optimization.
3) Analyze results and optimization effects, generate trade-off curves and charts with M-Explore
4) Document analog IP creation and re-use fully automatically using template-based documentation
5) Re-use IP by changing specs, migrate to new nodes, re-verification, optimization